#1 clean up v. put (things or places) in order; "Tidy up your room!". wn #2 clean up v. make a big profit; often in a short period of time; "The investor really cleaned up when the stock market went up". wn #3 clean up v. dispose of; "settle the bills". wn #4 clean up v. make oneself clean, presentable or neat; "Clean up before you go to the party". wn