#1 fret v. [fuss, niggle] worry unnecessarily or excessively; "don't fuss too much over the grandchildren--they are quite big now". wn
#2 fret v. be agitated or irritated; "don't fret over these small details". wn
#3 fret n. [stew, sweat, lather, swither] agitation resulting from active worry; "don't get in a stew"; "he's in a sweat about exams". wn
#4 fret n. [worn spot] a spot that has been worn away by abrasion or erosion. wn
#5 fret v. provide (a musical instrument) with frets; "fret a guitar". wn
vizzz