#1 lonesome s. [lone, only, sole, solitary] being the only one; single and isolated from others; "the lone doctor in the entire county"; "a lonesome pine"; "an only child"; "the sole heir"; "the sole example"; "a solitary instance of cowardice"; "a solitary speck in the sky". wn
#2 lonesome s. [lonely] marked by dejection from being alone; "felt sad and lonely"; "the loneliest night of the week"; "lonesome when her husband is away"; "spent a lonesome hour in the bar". wn
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