#1 mess up v. make a mess of, destroy or ruin; "I botched the dinner and we had to eat out"; "the pianist screwed up the difficult passage in the second movement". wn
#2 mess up v. disturb the smoothness of; "ruffle the surface of the water". wn
#3 mess up v. make a mess of or create disorder in; "He messed up his room". wn
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