#1 offend v. [pique] cause to feel resentment or indignation; "Her tactless remark offended me". wn
#2 offend v. [transgress, infract, violate, go against, breach, break] act in disregard of laws, rules, contracts, or promises; "offend all laws of humanity"; "violate the basic laws or human civilization"; "break a law"; "break a promise". wn
#3 offend v. [shock, scandalize, scandalise, appal, appall, outrage] strike with disgust or revulsion; "The scandalous behavior of this married woman shocked her friends". wn
#4 offend v. [hurt, wound, injure, bruise, spite] hurt the feelings of; "She hurt me when she did not include me among her guests"; "This remark really bruised my ego". wn
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