#1 pi n. the ratio of the circumference to the diameter of a circle; approximately equal to 3.14159265358979323846.... wn
#2 pi n. [private detective, PI, private eye, private investigator, operative, shamus, sherlock] someone who can be employed as a detective to collect information. wn
#3 pi n. [principal investigator, PI] the scientist in charge of an experiment or research project. wn
#4 pi n. the 16th letter of the Greek alphabet. wn
#5 pi n. [protease inhibitor, PI] an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs. wn
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