#1 take off v. leave; "The family took off for Florida". wn #2 take off v. take away or remove; "Take that weight off me!". wn #3 take off v. depart from the ground; "The plane took off two hours late". wn #4 take off v. take time off from work; stop working temporarily. wn #5 take off v. mimic or imitate in an amusing or satirical manner; "This song takes off from a famous aria". wn