definition of
[derangement]

[1] #1 derangement n. [mental unsoundness, unbalance] a state of mental disturbance and disorientation. wn

[2] #2 derangement n. [upset, overthrow] the act of disturbing the mind or body; "his carelessness could have caused an ecological upset"; "she was unprepared for this sudden overthrow of their normal way of living". wn